Publications

As part of our commitment to unparalleled scientific research – from discovery to invention – our scientists and postdoctoral research fellows are encouraged to be active members of the scientific community and have published papers in numerous peer-reviewed, thought-leading publications.

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2026 Publications

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June 20, 2026
SACI-IO HR+: A randomized phase II trial of sacituzumab govitecan with or without pembrolizumab in patients with metastatic hormone receptor-positive/HER2-negative breast cancer
Journal: Annals of Oncology
Authors:

Garrido-Castro, A C; Kim, S E; Li, T; Desrosiers, J; Nanda, R; Abdou, Y; Clark, A S; Sacks, R L; O'Connor, T; Sinclair, N; Lo, S; Augdahl, G; Wrabel, E; DiLullo, M; Rahman, T

Citation:

Journal: Annals of Oncology

June 20, 2026
Ovo, an open-source ecosystem for de novo protein design
Journal: Communications Biology
Authors:

Prihoda, David; Ancona, Marco; Calounova, Tereza; Kral, Adam; Polak, Lukas; Hrban, Hugo; Dickens, Nicholas J; Bitton, Danny A

Citation:

Journal: Communications Biology

June 20, 2026
Prolonged autophagy induction correlates with host cell protein reduction in CHO cell culture
Journal: Biotechnology Progress
Authors:

Sahoo, Ansuman; Tsukidate, Taku; Pendyala, Geetanjali; Yang, Rong-Sheng; Li, Xuanwen; Madabhushi, Sri Ranganayaki

Citation:

Journal: Biotechnology Progress

June 18, 2026
Targeting TROP2 in drug-tolerant persister cells delays EGFR tyrosine kinase inhibitor resistance in non-small-cell lung cancer
Journal: Cancer Cell
Authors:

Liao, Jun; Yao, Wenxiu; Yu, Yan; Li, Anlin; Huang, Jie; Li, Xingya; Sun, Longhua; Zhang, Yongchang; Wang, Yongsheng; Qu, Xiujuan; Zhao, Jun; Wang, Haiyong; Zhuang, Weitao; Hu, Liyang; Chen, Xueyuan

Citation:

Journal: Cancer Cell

June 18, 2026
Access to N2-Substituted (Aza)Indazoles
Journal: Organic Letters
Authors:

Fan, Flora; Niu, Xiangfeng; Su, Wanqi; Chan, Vincent S

Citation:

Journal: Organic Letters

June 18, 2026
Development of a High-Throughput Size-Exclusion Chromatography-Mass Spectrometry Workflow for Real-Time Monitoring of Bioconjugation of Cysteine-Based Antibody-Drug Conjugates
Journal: Bioconjugate Chemistry
Authors:

Zhang, Zhengqi; Jin, Pei-Ru; Lin, Wei; Liang, Tao; Deyanova, Ekaterina; Gunawan, Rico; Ren, Hong

Citation:

Journal: Bioconjugate Chemistry

June 17, 2026
CellVision: A Deep Learning based Image Analysis Platform to Accelerate Immuno-Plaque Assay Data Processing for Dengue Vaccine Development
Journal: SLAS Discovery
Authors:

Wang, Yi; Ngo, Michelle N; Wang, Shubing; Jarrah, Justin; Salami, Hossein; Hofmann, Carl; Joshi, Anjali; Skomski, Daniel; Loughney, John W

Citation:

Journal: SLAS Discovery

June 17, 2026
Overcoming doramectin failure: field efficacy of pour-on 5% fluralaner and an experimental 1% oral formulation for the prevention of Cochliomyia hominivorax-associated umbilical myiasis in newborn calves
Journal: Parasites & Vectors
Authors:

de Freitas, Murilo Damasceno Brunet; Rodrigues, Daniel de Castro; de Paiva, Pablo Eduardo Martins; Torres, Siddartha; Borges, Fernando de Almeida

Citation:

Journal: Parasites & Vectors

June 17, 2026
Synthetic Approaches to the New Drugs Approved During 2024
Journal: Journal of Medicinal Chemistry
Authors:

France, Scott P; Lindsey, Erick A; McInturff, Emma L; Berritt, Simon; Flick, Andrew C; Fink, Sarah; Gibson, Tony S; Gray, Kaitlyn; Hubbell, Aran K; Johnson, Amber M; Liu, Yiyang; Mahapatra, Subham; Watson, Rebecca B; Zhou, Zhiyao

Citation:

Journal: Journal of Medicinal Chemistry

June 16, 2026
Incidence of Recurrent Respiratory Papillomatosis (RRP) in Denmark and Sweden During 2000-2023: Two Nationwide Cohort Studies in Children and Young Adults
Journal: Open Forum Infectious Diseases, Volume: 13, Issue: 6
Authors:

Sundström, Karin; Munk, Christian; Wang, Jiangrong; Frederiksen, Kirsten; Kleppe, Sara Nordqvist; Mahale, Parag; Tota, Joseph E; Kjær, Susanne K

Citation:

Journal: Open Forum Infectious Diseases, Volume: 13, Issue: 6

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1-10 of 297

2025 Publications

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December 24, 2025
Effect of pembrolizumab on viral hepatitis load and transaminases in advanced hepatocellular carcinoma
Journal: Annals of Hepatology
Authors:

Chan, Stephen Lam; Finn, Richard S; Edeline, Julien; Ogasawara, Sadahisa; Knox, Jennifer J; Daniele, Bruno; Ryoo, Baek-Yeol; Merle, Philippe; Bouattour, Mohamed; Lim, Ho-Yeong; Chao, Yee; Yau, Thomas; Haber, Barbara Anne; Malhotra, Usha; Siegel, Abby B

Citation:

Journal: Annals of Hepatology

December 23, 2025
Polymers as Stabilizing Excipients for Spray-Dried Protein Formulations
Journal: Pharmaceutical Research
Authors:

Patil, Chanakya D; Huang, Yijing; Arte, Kinnari Santosh; Kafle, Navin; Renawala, Harshil K; Liu, Jiaying; Nie, Haichen; Zhou, Qi Tony; Qu, Li Lily

Citation:

Journal: Pharmaceutical Research

December 23, 2025
Once-Weekly Oral Islatravir Plus Lenacapavir Versus Daily Oral Bictegravir, Emtricitabine, and Tenofovir Alafenamide in Persons With HIV-1 : A Phase 2 Randomized Study
Journal: Annals of Internal Medicine
Authors:

Colson, Amy E; Crofoot, Gordon E; Ruane, Peter J; Ramgopal, Moti N; Dretler, Alexandra W; Nahass, Ronald G; Sinclair, Gary I; Berhe, Mezgebe; Roberts, Afsoon; Applin, Shauna; Brinson, Cynthia; Jayaweera, Dushyantha; Workowski, Kimberly A; Shihadeh, Fadi; Liu, Shan-Yu

Citation:

Journal: Annals of Internal Medicine

December 22, 2025
Predicting the ritonavir crisis by revisiting the polymorph landscape with crystal structure prediction and form 4 structure solution
Journal: Communications Chemistry, Volume: 8, Issue: 1
Authors:

Iuzzolino, Luca; Kelly, Andrew W; Chaudhry, Mohammad T; Jandl, Cristian; Stam, Danny; Lee, Alfred Y

Citation:

Journal: Communications Chemistry, Volume: 8, Issue: 1

December 22, 2025
AMPK Activation by MK-8722 Measured with 18FFDG-PET Imaging in Rodents and Non-Human Primates
Journal: Molecular Imaging and Biology
Authors:

Rubins, Daniel J; Meng, Xiangjun; Wang, Shubing; Haley, Hyking; Posavec, Diane; Purcell, Mona; Riffel, Kerry; Myers, Robert W; Sebhat, Iyassu K; Trotter, Dinko Gonzalez; Klimas, Michael; Holahan, Marie

Citation:

Journal: Molecular Imaging and Biology

December 22, 2025
INDUCE-3: A randomized Phase II/III study of first-line feladilimab plus pembrolizumab in patients with recurrent/metastatic head and neck squamous cell carcinoma
Journal: Clinical Cancer Research
Authors:

Rischin, Danny; Hansen, Aaron R; Cohen, Ezra E W; Tahara, Makoto; Harrington, Kevin J; Haddad, Robert I; Licitra, Lisa; Mehanna, Hisham; Ferris, Robert L; Koralewski, Piotr; Penkov, Konstantin; Schenker, Michael; Spigel, David R; Daste, Amaury; Hong, Min Hee

Citation:

Journal: Clinical Cancer Research

December 21, 2025
Society for Immunotherapy of Cancer: Standards for Reporting of Multiplex Immunohistochemistry/Immunofluorescence Assays (STORMI)
Journal: Journal for ImmunoTherapy of Cancer, Volume: 13, Issue: 12
Authors:

Sater, Sam; Bifulco, Carlo B; Rodriguez-Canales, Jaime; Yeong, Joe; Akturk, Guray; Angelo, Michael; Ballesteros-Merino, Carmen; Bankhead, Peter; Basu, Subham; Blando, Jorge M; Brajkovic, Saska; Cassano, Marco; Chen, Benjamin J; Coskun, Ahmet F; Cottrell, Tricia R

Citation:

Journal: Journal for ImmunoTherapy of Cancer, Volume: 13, Issue: 12

December 19, 2025
Randomized Phase 3 Trial Evaluating the Safety, Tolerability, and Immunogenicity of V114, a 15-Valent PCV, Followed by PPSV23 6 Months Later (PNEU-DAY): Subgroup Analysis in Adults 18-49 Years of Age Enrolled at Center for Indigenous Health Sites
Journal: Vaccines, Volume: 14, Issue: 1
Authors:

Hammitt, Laura L; Buchwald, Ulrike K; McCauley, Jennifer; Shekar, Tulin; Fu, Wei; Cheon, Kyeongmi; Sterling, Tina; Tamms, Gretchen; Banniettis, Natalie; Musey, Luwy; LeBlanc, Jason J; Weatherholtz, Robert; Riley, Dennie Parker; Denny, Estar; Tso, Carol

Citation:

Journal: Vaccines, Volume: 14, Issue: 1

December 19, 2025
Revolutionizing ELISA development: The transformative impact of automation on monoclonal antibody potency assays
Journal: Journal of Pharmaceutical and Biomedical Analysis, Volume: 271
Authors:

Xin, Xiaoran; Pung, Douglas; Hsu, Amy; Dey, Monisha; Wu, Qian; Feng, Bo; Sun, Dengyun; Gurney, Kevin; Ehrhardt, Anka

Citation:

Journal: Journal of Pharmaceutical and Biomedical Analysis, Volume: 271

December 18, 2025
A mitochondrial amidoxime-reducing component 1 (mARC1) A168T amino acid substitution does not confer protection from MASH and fibrosis in multiple mouse models of chronic liver disease
Journal: Biochemical Journal
Authors:

Pandovski, Sentibel; Yang, Tiffany; Zhou, Heather; Rosahl, Thomas W; Carballo-Jane, Ester; Talukdar, Saswata; Coyne, Erin S

Citation:

Journal: Biochemical Journal

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2024 Publications

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December 16, 2024
Current State and New Horizons in Applications of Physiologically Based Biopharmaceutics Modeling (PBBM): A Workshop Report
Journal: Molecular Pharmaceutics
Authors:

Tannergren, Christer; Arora, Sumit; Babiskin, Andrew; Borges, Luiza; Chatterjee, Parnali; Cheng, Yi-Hsien; Dallmann, André; Govada, Anitha; Heimbach, Tycho; Hingle, Martin; Kollipara, Sivacharan; Kotzagiorgis, Evangelos; Lindahl, Anders; Mackie, Claire; Malamatari, Maria

Citation:

Journal: Molecular Pharmaceutics

December 15, 2024
Development of a multiplexing method for the quantification of “high-risk” host cell lipases in biotherapeutics by Luminex
Journal: Analytica Chimica Acta, Volume: 1332
Authors:

Osko, Jeremy D; Rivera, Shannon; Wang, Fengqiang; Niedringhaus, Thomas

Citation:

Journal: Analytica Chimica Acta, Volume: 1332

December 13, 2024
High-Throughput Experimentation Reveals Scope and Limitations of Selective Phosphine Reductants and Enables One-Pot mAb Reduction/Conjugation
Journal: Organic Process Research & Development
Authors:

Emmert, Marion H; Yang, Cuixian; Kwan, Eugene E; Chmielowski, Rebecca; Kilgore, Bruce; Vanaernum, Zachary L; Bottecchia, Cecilia; Barrientos, Rodell C; Haley, Monica; Raymond, Kelly; Rauscher, Michael; Dunn, Zachary D; Desai, Jay

Citation:

Journal: Organic Process Research & Development

December 13, 2024
Post-column denaturation-assisted hydrophobic interaction chromatography-mass spectrometry for rapid and in-depth characterization of positional isomers in cysteine-based antibody-drug conjugates
Journal: Journal of Pharmaceutical and Biomedical Analysis, Volume: 255
Authors:

Zhang, Zhengqi; Liu, Anita P; Wang, Hongxia; Schuessler, Hillary A

Citation:

Journal: Journal of Pharmaceutical and Biomedical Analysis, Volume: 255

December 13, 2024
HTE-Enabled Development of an Ene-Reductase-Catalyzed Desymmetrization: Remote Control of All-Carbon Quaternary γ-Centers
Journal: Organic Letters
Authors:

Petrone, David A; Valette, Damien; Boyd, Olivia; Newman, Justin; Plasek, Erin; Shao, Guangxin; Wang, Xiao; Itoh, Tetsuji; Maddess, Matthew; Peng, Feng

Citation:

Journal: Organic Letters

December 12, 2024
A phase III randomized controlled non-inferiority trial to study the efficacy and safety of imipenem/cilastatin/relebactam (IMI/REL) versus piperacillin/tazobactam (PIP/TAZ) in patients with hospital-acquired bacterial pneumonia (HABP) or ventilator-associated bacterial pneumonia (VABP)
Journal: International Journal of Infectious Diseases
Authors:

Li, Junjie; Wei, Feng; Xiang, Peng; Tang, Zhengang; Ding, Lianshu; Chen, Luke Francis; Losada, Maria; Iamboliyska, Zlatka; Sun, Fang; Zhu, Mingfen; Guo, Xiaodan; Du, Xiaoling; Chen, Chang; Bruno, Christopher; Koseoglu, Sandra

Citation:

Journal: International Journal of Infectious Diseases

December 12, 2024
Optimizing public private partnerships to support clinical cancer research
Journal: JNCI Journal of the National Cancer Institute
Authors:

Herbst, Roy S; Blumenthal, Gideon; Khleif, Samir N; Lippman, Scott M; Meropol, Neal J; Rosati, Kristen; Shulman, Lawrence N; Smith, Heind; Wang, Meina; Winn, Robert A; Schilsky, Richard L

Citation:

Journal: JNCI Journal of the National Cancer Institute

December 12, 2024
Alkene Carboxy-Alkylation via CO2•
Journal: Journal of the American Chemical Society
Authors:

Dang, Y; Han, Jimin; Chmiel, Alyah F; Alektiar, Sara N; Mikhael, Myriam; Guzei, Ilia A; Yeung, Charles S; Wickens, Zachary K

Citation:

Journal: Journal of the American Chemical Society

December 11, 2024
General chemoselective hindered amide coupling enabled by TCFH-catalytic Oxyma and transient imine protection
Journal: Chemical Communications
Authors:

Li, Qiuhan; Napier, Sarah; Singh, Andrew N; Vickery, Thomas P; Fan, Yi; Hernandez, Edgar; Wang, Tao; Dalby, Stephen M

Citation:

Journal: Chemical Communications

December 10, 2024
Extracting Orientation and Distance-Dependent Interaction Potentials between Proteins in Solutions Using Small-Angle X-ray/Neutron Scattering
Journal: The Journal of Physical Chemistry Letters
Authors:

Liu, Yun; Hatch, Harold W; Yuan, Guangcui; Shen, Vincent K; Grishaev, Alexander V; Panchal, Jainik; Blanco, Marco

Citation:

Journal: The Journal of Physical Chemistry Letters

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1-10 of 737

2023 Publications

No search results found.
December 14, 2023
Use of a Dynamic Flow Platform To Translate a Batch Immobilized Transaminase Process to a Packed Bed Reactor for the Synthesis of an Intermediate of Nemtabrutinib
Journal: Organic Process Research & Development
Authors:

Di Maso, Michael J; Kuethe, Jeffrey T; Narsimhan, Karthik; Burris, Matthew; Chung, Cheol K; DiBenedetto, Michael; Forstater, Jacob H; Grosser, Shane T; Kuhl, Nadine; Levesque, Francois; Maguire, Anne; Maloney, Kevin M; McMullen, Jonathan P; Prier, Christopher K; Qi, Ji

Citation:

Journal: Organic Process Research & Development

December 14, 2023
Demonstrating the importance of porcine reproductive and respiratory syndrome virus papain-like protease 2 deubiquitinating activity in viral replication by structure-guided mutagenesis
Journal: PLoS Pathogens, Volume: 19, Issue: 12
Authors:

Bailey-Elkin, Ben A; Knaap, Robert C M; De Silva, Anuradha; Boekhoud, Ilse M; Mous, Sandra; van Vught, Niek; Khajehpour, Mazdak; van den Born, Erwin; Kikkert, Marjolein; Mark, Brian L

Citation:

Journal: PLoS Pathogens, Volume: 19, Issue: 12

December 11, 2023
Epilepsy-linked kinase CDKL5 phosphorylates voltage-gated calcium channel Cav2.3, altering inactivation kinetics and neuronal excitability
Journal: Nature Communications, Volume: 14, Issue: 1
Authors:

Sampedro-Castañeda, Marisol; Baltussen, Lucas L; Lopes, André T; Qiu, Yichen; Sirvio, Liina; Mihaylov, Simeon R; Claxton, Suzanne; Richardson, Jill C; Lignani, Gabriele; Ultanir, Sila K

Citation:

Journal: Nature Communications, Volume: 14, Issue: 1

December 6, 2023
A questionnaire-based survey in Spain provides relevant information to improve the control of ovine coccidiosis
Journal: Frontiers in Veterinary Science, Volume: 10
Authors:

Sánchez-Sánchez, Roberto; Gutiérrez, Jorge; Blasco-Castello, José Luis; Marcos-Santamaría, María; Cano-Alsua, Santiago; Elvira, Laura; Ferre, Ignacio; Ortega-Mora, Luis Miguel

Citation:

Journal: Frontiers in Veterinary Science, Volume: 10

December 5, 2023
Cu Oxamate-Promoted Cross-Coupling of α-Branched Amines and Complex Aryl Halides: Investigating Ligand Function through Data Science
Journal: ACS Catalysis, Volume: 13, Issue: 24
Authors:

Matthews, Adrian D; Peters, Ellyn; Debenham, John S; Gao, Qi; Nyamiaka, Maya D; Pan, Jianping; Zhang, Li Kang; Dreher, Spencer D; Krska, Shane W; Sigman, Matthew S; Uehling, Mycah R

Citation:

Journal: ACS Catalysis, Volume: 13, Issue: 24

December 5, 2023
Copper-Catalyzed Benzylic C-H Cross-Coupling Enabled by Redox Buffers: Expanding Synthetic Access to Three-Dimensional Chemical Space
Journal: Accounts of Chemical Research, Volume: 56, Issue: 24
Authors:

Chen, Si-Jie; Krska, Shane W; Stahl, Shannon S

Citation:

Journal: Accounts of Chemical Research, Volume: 56, Issue: 24

December 4, 2023
Cloud security in a bioanalytical world: considerations for use of third-party cloud services for bioanalysis
Journal: Bioanalysis, Volume: 15, Issue: 24
Authors:

Davis, Scott; Mitra-Kaushik, Shibani; Woolf, Eric; Evens, John; Dawes, Michelle; Kentner, Jason; Subbarao, Nanda; Sundman, Phillip; Rusnak, David

Citation:

Journal: Bioanalysis, Volume: 15, Issue: 24

December 1, 2023
Risk of Phase Incoherence in Wide Area Control of Synchronous Power Networks With Time-Delayed and Corrupted Measurements
Journal: IEEE Transactions on Automatic Control, Volume: 68, Issue: 12
Authors:

Somarakis, Christoforos; Liu, Guangyi; Motee, Nader

Citation:

Journal: IEEE Transactions on Automatic Control, Volume: 68, Issue: 12

December 1, 2023
FRESH™ 3D bioprinted cardiac tissue, a bioengineered platform for in vitro pharmacology
Journal: APL Bioengineering, Volume: 7, Issue: 4
Authors:

Finkel, Samuel; Sweet, Shannon; Locke, Tyler; Smith, Sydney; Wang, Zhefan; Sandini, Christopher; Imredy, John; He, Yufang; Durante, Marc; Lagrutta, Armando; Feinberg, Adam; Lee, Andrew

Citation:

Journal: APL Bioengineering, Volume: 7, Issue: 4

December 1, 2023
Lenvatinib plus pembrolizumab versus lenvatinib plus placebo for advanced hepatocellular carcinoma (LEAP-002): a randomised, double-blind, phase 3 trial
Journal: The Lancet Oncology, Volume: 24, Issue: 12
Authors:

Llovet, Josep M; Kudo, Masatoshi; Merle, Philippe; Meyer, Tim; Qin, Shukui; Ikeda, Masafumi; Xu, Ruocai; Edeline, Julien; Ryoo, Baek-Yeol; Ren, Zhenggang; Masi, Gianluca; Kwiatkowski, Mariusz; Lim, Ho Yeong; Kim, Jee Hyun; Breder, Valeriy

Citation:

Journal: The Lancet Oncology, Volume: 24, Issue: 12

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