Health awareness

Know your risk for bladder cancer — and don’t ignore the signs

Awareness gaps can impact recognition and diagnosis of bladder cancer

May 4, 2026

Share this article

When bladder cancer is found early, before it spreads beyond the bladder, patients have more treatment options. That’s why we’re focused on getting to the heart of what people need to hear. Especially those at risk of bladder cancer.

“Too many patients don’t recognize the warning signs for bladder cancer or feel comfortable talking about them. Breaking that silence is just as important as developing new treatments — because awareness is the first step toward helping to save lives.”

• Dr. M. Catherine Pietanza
  Vice president, global clinical development, MSD Research Laboratories
  

Bladder cancer risk is not largely based on family genetics

Some people inherit certain genes from their parents that can increase their risk of bladder cancer. But bladder cancer doesn’t often run in families, and inherited genes are not thought to be a major cause of this disease. Most gene changes linked to bladder cancer develop during a person’s life, rather than having been inherited.

Don’t ignore blood in your urine or changes in your urinary habits — talk to your doctor right away

Bladder cancer can often be found early because it can cause symptoms that lead a person to see a healthcare provider. Blood in your urine is usually the first sign, before pain or other symptoms appear. In most cases, blood in the urine doesn’t mean you have bladder cancer, but it’s important to see your doctor to rule out other causes like a bladder or kidney stone, an infection or kidney disease.

Be aware of your risks for bladder cancer

Knowing and avoiding the risk factors that are within your control may help lower your risk of bladder cancer. Among risk factors for bladder cancer, smoking is highest on the list — causing about half of all bladder cancers. Exposure to other chemicals can also raise risk over time, including industrial chemicals used in making rubber, leather, textiles and paint products, as well as in printing companies. People who work as painters, firefighters, hairdressers and truck drivers can similarly be exposed to certain chemicals and fumes that might increase their risk of bladder cancer.

Some risk factors can’t be controlled, but you may be able to help lower your risk of bladder cancer by not smoking, practicing good work safety practices, limiting exposure to toxins (like arsenic), staying well hydrated and eating plenty of fruits and vegetables.

Know your individual risk factors and talk to your doctor to see if you are at high risk for bladder cancer. If you have risk factors that strongly increase your risk of bladder cancer, and you’ve noticed certain changes in your urine, your doctor may recommend tests to look for bladder cancer.

“Our goal is to reach patients sooner — before the disease advances, before options narrow.”

• Dr. M. Catherine Pietanza

When bladder cancer is found early, there are more treatment options. In later stages of bladder cancer, removing the bladder may need to be part of the treatment plan.

This is where our focus begins: breaking the silence and encouraging people to talk to their doctor right away if they notice any possible symptoms.

In 2023, Jon Michaels was happily balancing the joys and routines of life – from his publishing job and his passion for music as a singer-songwriter to cherishing moments with his wife, Jeannie, and their daughter, Jennings.

One day, Michaels noticed a painless lump in his neck. Since it didn’t affect his ability to sing, talk, eat or drink, he initially dismissed it. When the lump persisted, he was urged to see a doctor who conducted a biopsy and surgically removed the lump. Then came the news that changed his life forever – Michaels was diagnosed with head and neck cancer. He now had to face the impact of this diagnosis on his life, his loved ones – and his music.

“I was wondering, ‘How would I react if I were to be diagnosed with cancer?’” he said. “That day, I found out.”

What is head and neck cancer?

Head and neck cancer describes tumors that develop in or around the throat, larynx, nose, sinuses and mouth. In 2022, there were more than 947,000 cases of head and neck cancer worldwide. These data include cancers of the salivary glands, hypopharynx, oropharynx, nasopharynx, larynx, lip and oral cavity. Michaels’ diagnosis, squamous cell carcinoma of the head and neck, is the most common type of head and neck cancer and begins in the flat, squamous cells that make up the thin mucosal lining of the head and neck.

Michaels’ painless lump is a common symptom of this disease. Other symptoms may include a sore in the mouth that won’t heal, coughing up blood and pain when swallowing.

The power of support in Michaels’ cancer fight

After his diagnosis, Michaels and his wife discussed a treatment plan with the doctor.

“He started by saying, ‘I have good news and bad news. The good news was that we can treat your cancer, with surgery, radiation and chemotherapy. The bad news is that it will be tough,’” Michaels said. “That was hard to process.”

As Michaels started treatment, he was concerned about how it may affect his ability to pursue music.

“That worried me, as music was so much a part of my life,” he said.

Michaels faced both physical and emotional challenges during his treatment, reaching a point where he almost wanted to give up.

However, his wife refused to let him. She inspired him to remain strong and encouraged him to accept help during this difficult time. Even his therapist advised him: “Let the people who love you, love you.” Those words taught Michaels to accept support from his neighbors, friends and family.

“My support group were the real heroes in this experience,” he said.

While others handled life’s daily tasks for him, such as sending meals, mowing the lawn, helping with chores and transportation to appointments, Michaels focused on fighting this disease.

These acts of kindness got him through his toughest days, allowing him to recover and channel his emotions into music, even writing a song to reflect on his cancer experience.

SEE ALSO: Supporting colleagues with cancer

Strengthening our commitment to patients with cancer

Stories of support, like Michaels’, underscore why patients are our inspiration as we continue to pursue the fight against cancer. His journey is an important reminder to turn to a supportive network during trying times.

“The most rewarding part was the overwhelming love shown by my family, friends and strangers,” he said. “Trust in the care and fight when they tell you to fight.”

Health awareness

From awareness to action: understanding triple negative breast cancer (TNBC)

Early detection is important for this aggressive type of breast cancer. Learn more about the risk factors, signs and symptoms of TNBC.

October 28, 2025

Share this article

There are many different types and subtypes of breast cancer — defined by where it starts in the breast, how much it has grown or spread and how it behaves. One of the more aggressive and difficult-to-treat types is triple-negative breast cancer (TNBC), and knowing the facts is one of the most important steps in a patient’s cancer journey.

What is TNBC?

Breast cancer tumors may be tested for three receptors, or proteins, that make cancer grow. A TNBC diagnosis is made when the tumor tests negative for estrogen and progesterone receptors and does not over express HER2.

TNBC differs from other types of invasive breast cancer, as it tends to grow and spread faster, with a worse prognosis for patients. It also has a high likelihood of recurrence.

Who’s at risk of developing TNBC?

While TNBC can affect anyone, some people may be at higher risk. Factors that make someone more likely to be diagnosed with TNBC include:

• Sex: People assigned female at birth are at higher risk for TNBC compared to people assigned male at birth
• Race/ethnicity: TNBC disproportionately impacts Black women
• Age: TNBC is more common in women younger than 40
• Genetic mutations: Mutations in certain genes are associated with TNBC

What are the signs and symptoms of TNBC?

TNBC may have the same signs and symptoms as other common types of breast cancer, though most breast cancers are detected before symptoms appear through regular screenings.

Possible signs and symptoms of breast cancer may include:

• A new breast lump or mass
• Swelling of all or part of a breast
• Skin dimpling
• Breast or nipple pain
• Nipple retraction
• Nipple or breast skin that’s red, dry, flaking or thickened
• Nipple discharge
• Swollen lymph nodes, under the arm or near the collar bone

Our commitment to access to health

Navigating breast cancer, especially aggressive types like TNBC, can be daunting and for some — overwhelming. However, access to information and the right tools and resources can contribute to a more equitable patient journey for those impacted. By equipping patients to make better informed decisions, we can help them to advocate and determine the best path forward.

Early detection of breast cancer isn’t just important — it could be life-saving. That’s why we’re focused on helping women get the care they need.

— Josette Gbemudu

AVP, patient health innovation.

“We focus our work on making the most impact for patients — from advancing science to help patients living with this condition to creating patient-friendly education materials. We’re committed to the needs of people living with breast cancer, globally,” said Karen Lisa Smith, senior principal scientist.

Learn more about our commitment to expanding access to health.