Content Topic: Health Awareness

Health Awareness

Make time to get screened for cancer

Find out why it's important to follow cancer screening recommendations

January 15, 2025

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We’ve all had the feeling that there aren’t enough hours in the day. In between everything else on the to-do list, it can feel hard to make your health and annual appointments a priority. However, it’s important to take control of your health and talk to your doctor about what cancer screenings might be recommended for you.

Why timing matters in cancer screening

Time is important with a cancer diagnosis so that treatment can be started early, before cancer has spread to other parts of the body. Cancer screenings can increase the chance of finding disease before a person has symptoms or when cancer is still in earlier stages.

There are screening guidelines for many types of cancer, such as breast, colorectal and lung cancer, as well as melanoma. Screening recommendations often take into consideration a few factors, such as age, family history and lifestyle. Your doctor can help you identify which screenings might be right for you.

As a leader in oncology, we’re committed to addressing the global impact of cancer.

“Through our work to increase access to screening and our other initiatives and programs, we appreciate the importance of finding disease early, before it has spread to help enable early treatment, because we believe people with cancer deserve more,” said Linda Kollmar, associate vice president, medical affairs, value and implementation.

So, make time now to talk to your doctor and to find out if you’re eligible for cancer screening.

We’re working to help address other barriers to cancer screening

Raising awareness about cancer screening is just one way our company works to help improve lives. We also strive to help address barriers to screening and treatment, which is why we work with partners around the globe to support public health initiatives that support recommended screening and create access to high quality cancer care for all patients.

Our support of the American Cancer Society’s Get Screened initiative makes it possible for community members to be screened for breast, cervical, colorectal and lung cancer who might not have access otherwise. And working with City Cancer Challenge, we support the Patient Navigation Program in Kigali, Rwanda to train nurses as patient navigators who can help people understand health information more easily and gain access to health care options more quickly.

Find out more about how we collaborate with partners around the world to help make cancer care more accessible.

Health Awareness

Debunking type 2 diabetes misconceptions

Learn more about type 2 diabetes

November 8, 2024

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While diabetes is a major health concern, there are common misconceptions around type 2 diabetes diagnosis and management that should be addressed.

What is type 2 diabetes?

Type 2 diabetes is characterized by resistance to insulin, a hormone produced by the pancreas, which helps glucose get into the body’s cells to be used for energy. In people with type 2 diabetes, the body isn’t able to properly use insulin, which allows too much glucose to build up in the blood and causes high blood sugar.

Here are some type 2 diabetes misconceptions explained.

01.

Misconception: Type 2 diabetes is not a serious disease.

Explanation: Type 2 diabetes should be taken seriously. If type 2 diabetes is not managed properly, it may lead to serious complications over time. Diabetes management, including learning about the condition, adopting a healthy lifestyle and working with a health care provider to create a treatment plan, can help decrease the risk of long-term complications.

02.

Misconception: If you have type 2 diabetes, the symptoms are obvious.

Explanation: Type 2 diabetes symptoms may develop slowly, often over several years, and can be so mild that it’s easy for symptoms to go unnoticed. Many people have no diabetes symptoms at all.

Type 2 diabetes symptoms may include:

  • Excessive thirst and/or hunger
  • Frequent urination
  • Blurred vision
  • Numbness or tingling in the hands and/or feet
  • Fatigue
  • Cuts and bruises that are slow to heal

03.

Misconception: All people with type 2 diabetes are overweight.

Explanation: While research shows that people who are overweight and who are not physically active are more likely to develop type 2 diabetes, there are other personal and lifestyle factors that can increase a person’s risk of developing the condition, including:

  • Age (45 years or older)
  • First degree family history (mother, father, sister, brother)
  • Ethnicity (African Americans, Hispanic/Latinx Americans, American Indians, Alaska Natives and some Pacific Islanders and Asian Americans are at higher risk)

04.

Misconception: If a family member has type 2 diabetes, you’ll also develop type 2 diabetes.

Explanation: If your mother, father, sister or brother has type 2 diabetes, you may have an increased risk for developing type 2 diabetes. However, this is only one of several risk factors. Adopting healthy lifestyle habits may help reduce your risk.

05.

Misconception: Type 2 diabetes only affects blood sugar.

Explanation: People with type 2 diabetes are twice as likely to have heart disease or a stroke. However, there are steps that can be taken to help reduce the risk of some of the more serious complications. These include keeping blood sugar levels as close as possible to a person’s individualized goal, eating healthy foods, exercising regularly, and maintaining blood pressure and cholesterol at levels set by a health care professional.

06.

Misconception: Type 2 diabetes can be cured.

Explanation: There’s no cure for type 2 diabetes as for many, it’s a progressive disease. However, there are some lifestyle changes that can help manage the condition, including making healthy food choices and increasing physical activity. Choose whole, minimally processed foods, such as fruits, non-starchy vegetables, whole grains, lean proteins and low-fat or skim milk cheese, as well as water over juice. Pay attention to how much you are eating, as larger portion sizes mean more calories. Additionally, exercise has been shown to improve blood glucose control, reduce cardiovascular risk factors and contribute to weight loss. Lifestyle changes alone may not be enough to control blood sugar. That’s why it’s important to work with your health care provider to develop an individualized treatment plan.

Health Awareness

Learn more about invasive pneumococcal disease and how infection spreads

Invasive pneumococcal disease can lead to a number of serious consequences in children

November 4, 2024

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What is invasive pneumococcal disease?

Invasive pneumococcal disease (IPD) is an infection caused by a bacteria called Streptococcus pneumoniae. It can lead to a number of serious illnesses including pneumococcal bacteremia (an infection of the blood) and pneumococcal meningitis (an infection of the coverings of the brain and spinal cord).

Children under the age of 2 and those with certain underlying medical conditions are particularly vulnerable to invasive pneumococcal infection, according to the World Health Organization (WHO).

~100

different types of S. pneumoniae, called serotypes, exist; however, a smaller number are responsible for most cases of IPD in children

75%

of IPD cases occur in children under 2 years of age, on average, according to a 2019 paper by the WHO

How does pneumococcal infection spread?

Pneumococcal bacteria can spread anywhere, anytime through close contact with respiratory secretions, like those produced from coughing or sneezing. Children can carry the bacteria in their nose or throat without demonstrating signs of illness.

Pneumococcal infections are more common during winter and early spring, when respiratory diseases are more prevalent.

What you can ask your pediatrician about pneumococcal infection:

  • Is my child at risk for invasive pneumococcal disease?
  • How could invasive pneumococcal disease harm my child?
  • What can I do to help reduce the risk of invasive pneumococcal disease for my child?

“There are steps people can take to be proactive about their family’s health. Parents should speak with their health care providers to learn more about invasive pneumococcal disease and the serious consequences it can cause.”

  • Dr. Ulrike Buchwald, scientific associate vice president, clinical research
Health Awareness

Driving prostate cancer research forward

Our scientists are dedicated to advancing research for potential treatment options for people diagnosed with prostate cancer

September 6, 2024

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It’s estimated that nearly 1.5 million people assigned male at birth were diagnosed with prostate cancer in 2022 worldwide.

But these patients aren’t just a statistic or a number. They’re our partners, our parents, our children, our siblings and our friends. They’re our loved ones, fighting for better outcomes and a chance for the future. And that’s who we’re fighting for, too.

“Globally, someone is diagnosed with prostate cancer nearly every minute. That’s why we’re working with urgency to advance research and provide potential treatment options for patients living with this disease.”

  • Dr. Kentaro Imai, distinguished scientist, oncology, prostate clinical research

The impact of prostate cancer on patients

Prostate cancer is the second most commonly diagnosed cancer and the fifth leading cause of cancer death in patients assigned male at birth worldwide. The average age at diagnosis is 66 years old. Prostate cancers is more likely to develop among those with African ancestry or a family history of the disease.

Prostate cancer can be genetic in other ways, too. Several inherited genetic mutations — such as those of the BRCA1 or BRCA2 genes — can increase prostate cancer risk. These types of genetic mutations, among others, can be identified through testing your tumor (also known as biomarker testing).

For those patients who are diagnosed with early stage prostate cancer, the prognosis is promising, with a five-year survival rate of nearly 100%. However, for patients with prostate cancer at an advanced stage, the outcomes can be dramatically different, and the five-year survival rate remains low.

“As with many cancers, patients with prostate cancer have the greatest chance of survival when their disease is detected early,” said Dr. Imai. “The prognosis for prostate cancer worsens as it spreads to other areas of the body, given that there are limited treatment options at that stage. It’s critical that we push forward to identify new options for these patients.”

Our commitment to prostate cancer research

Our science, coupled with new insights into the disease, continues to guide us as we pursue clinical advancements in prostate cancer.

"Our scientists are working diligently each and every day in an effort to discover new solutions for patients with prostate cancer."

— Dr. Kentaro Imai

Distinguished scientist, oncology, prostate clinical research

Since the next breakthrough can come from anywhere or anyone, we regularly collaborate across the entire prostate cancer community, working with health care providers, other companies, academia and advocates to gain a deeper understanding and make progress for patients with prostate cancer.

“The fight against prostate cancer is constantly evolving, and therefore our approach to the disease must evolve, as well,” said Dr. Imai. “We’re committed to pushing boundaries in pursuit of breakthrough advances that have the potential to change the lives of patients living with prostate cancer.”

Health Awareness

Understanding lung cancer: 5 essential things to know as a patient or caregiver

What to know about one of the most common types of cancer

August 21, 2024

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Lung cancer is one of the most commonly diagnosed cancers worldwide. In 2022, it was estimated that more than 2.4 million people globally were diagnosed with lung cancer.

Lung cancer is also the leading cause of cancer death worldwide. Nearly one-in-five (19%) cancer-related deaths were estimated to result from the disease worldwide in 2022.

Despite how common lung cancer is and its high mortality rates, there are still many misconceptions about the disease. Having accurate information is a critical step in the fight against lung cancer.

Our company is working for these patients and their families by advancing research and fostering greater awareness and understanding of the disease.

Here are five facts about lung cancer that we think patients or caregivers need to know.

01.

Every person with lung cancer deserves compassion and support.

People with lung cancer can face social stigma because they may have smoked. But the truth is, there’s no room for blame. People with lung cancer are worthy of all the compassion and support their families, health care teams and the wider cancer community can provide to help them stand against this disease.

Caregiver holding patient's hand

02.

It takes a village to navigate life with lung cancer.

When coping with a lung cancer diagnosis, it’s important to build a circle of support that includes the oncologist, health care teams, family and friends.

Connecting with others can provide a sense of support and comfort to help patients through everything that goes into managing this disease.

03.

There’s no one type of person who develops lung cancer.

Lung cancer strikes both men and women. While it is mostly diagnosed in older people, younger people can develop the disease. In fact, in 2022, more than 312,000 cases of lung cancer were estimated to be diagnosed worldwide among people 54 and younger.

Crowded street downtown

04.

There are multiple risk factors for lung cancer, including some outside our control.

Smoking is the greatest risk factor for developing lung cancer, but there are others as well, including having a family history of the disease and exposure to certain environmental substances. Worldwide, it is estimated that 10-25% of patients with lung cancer have never smoked with even higher proportions based on ethnicity and geographic region.

Environmental risks include:

  • Exposure to radon gas.
  • Exposure to occupational carcinogens, such as asbestos.
  • Exposure to outdoor air pollution, such as second-hand smoke, arsenic, chromium and nickel.

05.

Scientific advances are helping to make an impact in treating lung cancer.

Over the last 20 years, significant strides have been made to improve patient outcomes in the treatment of lung cancer. Key advancements include the development of targeted therapies, the incorporation of biomarker testing into standard practice and the progress of research that may offer promising breakthroughs for patients with difficult-to-treat tumor types.

Health Awareness

HPV and related cancers: What you need to know

Human papillomavirus (HPV) is a leading cause of certain types of cervical cancer and other cancers in men and women

August 15, 2024

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What is human papillomavirus (HPV)?

Human papillomavirus (HPV) is the most common sexually transmitted infection (STI).

For most people, HPV clears on its own. But for the very few who do not clear the virus, it can cause certain cancers and other diseases in both men and women. Unfortunately, there’s no way to know who will or will not clear the virus.

What cancers and diseases can be caused by HPV?

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HPV can cause certain types of:

  • cervical cancers
  • anal cancers
  • vulvar cancers
  • vaginal cancers
  • head and neck cancers
  • genital warts

The impact of HPV-related cancers

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~666,000 men and women were diagnosed with certain HPV-related cancers in 2018 worldwide

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As of 2022, cervical cancer was the 4th most common cancer in women worldwide

“There are steps people can take to be proactive about their health. Men and women should speak with their health care providers to learn more about the link between HPV and certain cancers and diseases.”

— Mel Kohn, M.D., M.P.H., executive director of medical affairs, MSD

The World Health Organization’s (WHO) movement towards cervical cancer elimination

Important steps have been taken to achieve a world where fewer women are affected by cervical cancer, but more needs to be done.

In 2020, the World Health Assembly adopted the global strategy to accelerate the elimination of cervical cancer as a public health problem.

To help achieve this goal, the WHO provides guidance and tools to support countries in implementing strategies and addressing challenges associated with cervical cancer prevention.

Health Awareness

Prostate cancer: stigma, early screening and support

A prostate cancer survivor and a caregiver and advocate want to inspire more people to talk about the disease

June 26, 2024

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Even after losing his father and grandfather to prostate cancer, Henry H. Washington III, Ph.D., was still shocked by his prostate cancer diagnosis after a routine screening. A retired Army Major and longtime athlete, Washington saw himself as the picture of health.

“After fighting for my country in the military and then to find out I have prostate cancer – how do I deal with that? It was a lot of emotions. I think as men we aren’t allowed to have emotions. We are taught that we need to be strong.”

  • Henry H. Washington III

Screening for prostate cancer is key in early detection

After skin cancer, prostate cancer is the second most common cancer for men in the U.S. Anyone who was born with a prostate can develop it. About 1 in 8 men will be diagnosed during their lifetime, and Black men are more likely to develop prostate cancer.

 In its early stages, prostate cancer can be difficult to identify because there are usually no symptoms.

Routine screening for those who are at risk can help detect prostate cancer early before it has spread. The greatest risk factor is age. Men over the age of 65 have the highest risk. Additional risk factors include inherited gene mutations and a family history of certain cancers.

Speaking out and supporting loved ones with prostate cancer

Courtney Bugler, president and CEO of ZERO Prostate Cancer who herself is a cancer survivor, said she was inspired to take on this role to support her father, who is living with the disease.

“There’s a stigma around prostate cancer and watching my dad made me want to shine a light on something that, quite honestly, I don’t think gets enough attention. After almost 20 years of him supporting me after my own diagnosis, it’s time for me to be there for him.”

  • Courtney Bugler
    CEO of ZERO Prostate Cancer

The stigma associated with prostate cancer can be attributed in part to the nature of the disease and its treatment disrupting normal urinary, bowel and sexual function, all of which can impact a patient’s body image and self-esteem. The thought of impaired sexual health, in particular, may even lead men to avoid screening for prostate cancer altogether.

Statistics show there’s still unease around prostate cancer diagnosis

A 2022 study of 200 metastatic prostate cancer patients, conducted by MSD and Cerner Enviza, found:

  • 58% of patients agree there’s a stigma around prostate cancer.
  • 39% didn’t share their feelings about having prostate cancer with loved ones because they felt they needed to “stay strong.”
  • More than a third felt uncomfortable, embarrassed or vulnerable talking to their loved ones (37%) or their doctor (38%) about emotional challenges.

Now cancer-free for a decade, Washington said he sees helping others as his purpose. He faces the potential unease head-on by educating others about prostate cancer, encouraging men to get checked early and working with men who have been diagnosed.

“Survivorship is not a linear experience; sometimes it’s two steps forward, five steps back,” said Washington. “The support I received from my friends, my support groups, my mother and my family is what gave me strength to educate others about prostate cancer.”

"Finding support and having people beside you who know what you're going through is what will help get you through.”

For more information about prostate cancer and access to helpful resources visit ZERO Prostate Cancer.

Health Awareness

How we can strengthen vaccination programs and build vaccine confidence together

Two MSD leaders share how we’re working to help protect communities from vaccine-preventable illnesses

February 21, 2024

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Vaccines are one of the most significant public health achievements in modern history, playing a vital role in helping to prevent certain infectious diseases and protect communities across the globe.

Unfortunately, the COVID-19 pandemic brought forth a new set of challenges in sustaining vaccination efforts for other preventable diseases — highlighting existing disparities and inequalities in access to health care and underscoring the urgent need for action.

In two op-eds for Devex, an independent news organization covering global development, Drew Otoo, Pharm.D., president of global vaccines, and Alfred Saah, M.D., executive director of scientific affairs, highlighted some of the ways we’re working to address these challenges at the global, national and local levels.

Collaborating to help increase health equity

Otoo said collaboration across sectors is key to building trust, enabling equity and establishing stronger, more resilient vaccination programs.

“Now more than ever, we have an opportunity to evaluate and strengthen our approach… Together, we can help create a more equitable future where vaccines are available to and accepted by all who can benefit from them.”

  • Drew Otoo, Pharm.D.
    President of global vaccines, MSD

Otoo shared examples of our work with local and global stakeholders to develop tailored approaches to improve vaccine confidence and supply vaccines for communities that might otherwise be without them:

  • Local organizations and community leaders have a deep understanding of the issues contributing to inequities and low routine vaccination rates in their communities, and they’re essential to identifying and executing solutions. We know this to be the case from our efforts through ImmUNITY Chicago, an initiative we helped catalyze with local stakeholders to address lower vaccination rates among neighborhoods in the Southwest Side of Chicago, predominantly among communities of color.
  • Strategic global collaborations are also critical to enabling stronger, more sustainable vaccination programs. We work with Gavi, the Vaccine Alliance — a global alliance that has helped to vaccinate nearly half of the world’s children in low-income countries.

Combating vaccine hesitancy and building trust

Saah emphasized our commitment to addressing vaccine hesitancy (the reluctance or refusal to vaccinate despite the availability of vaccines) and building confidence at local, national and global levels.

“By understanding the knowledge gaps and prioritizing strategies that strengthen how we communicate…we can potentially combat vaccine hesitancy, improve vaccine confidence and make a difference in global public health.”

  • Alfred Saah, M.D.
    Executive director of scientific affairs, MSD

Despite the well-documented benefits of vaccines, hesitancy is a longstanding public health issue that can result in under-vaccination and global disease outbreaks. The reasons behind vaccine hesitancy are often connected to the 3Cs Model, defined by a World Health Organization strategic advisory group:

  • Complacency: The perception that vaccine-preventable diseases pose little risk to individuals.
  • Convenience: The degree to which vaccination services are accessible.
  • Confidence: The degree to which an individual believes vaccines work, are safe and effective and are part of a trustworthy public health and medical system.

Saah shared some of our efforts to improve vaccine confidence, which include:

  • Working with collaborators to reach the global population and engage communities through mediums that resonate, such as social media, and through messages that can be delivered by trusted community members.
  • Building capabilities for our colleagues in local markets to better understand the strengths and vulnerabilities of vaccination programs on a global and national scale.

Continuing our work to improve vaccine access

Despite the challenges ahead, both Saah and Otoo are optimistic about the future.

“Combating vaccine hesitancy is not an easy feat and has been a challenge our global society has faced for centuries,” wrote Saah. “However, these challenges bring new opportunities to improve our approach and be better advocates for ourselves, our families and our communities.”

“By going where the need exists and continuing to invest in innovative, strategic and diverse collaborations, I'm confident we'll find new ways to solve complex public health problems.”

— Drew Otoo

Learn more about how collaborations can help yield stronger vaccination programs.

Health Awareness

‘Wonder Angie’ enlists her ‘super friends’ to fight oral cancer

After receiving an oral squamous cell carcinoma diagnosis, a head and neck cancer survivor finds hope by embracing science, prioritizing mental health and leaning on her work family

January 26, 2024

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Wonder Angie headshot

In 2017, Maria Angelica Rosario Marquez — or Angie, as she likes to be called— joined MSD in Colombia as a clinical data specialist. She had lost her father the year before and was looking forward to starting a new chapter. The novelty of that first year, however, was short-lived, as her mother was diagnosed with cancer in 2018.

Angie spoke to her manager, and he encouraged her to put family first. She booked a ticket to Chile and was there to support her mother and sister during the illness and her mother’s passing.

Just five months later, 34-year-old Angie was diagnosed with head and neck cancer, specifically squamous cell carcinoma of the tongue.

Head and neck cancer includes cancer of the oral cavity, throat (pharynx), voice box (larynx), nose (nasal cavity), sinuses (paranasal sinuses), and salivary glands. In 2020, nearly 932,000 people were diagnosed with a head and neck cancer globally. Some risk factors that may contribute to the development of head and neck cancer include tobacco use and alcohol consumption – but Angie’s disease was not linked to these typical risk factors.

It all started with pain in Angie’s tongue

Angie developed bruxism (grinding, clenching or gnashing of the teeth) and also noticed that she was continuously biting the same spot on her tongue while she was sleeping. She assumed it was due to stress caused by the devastation of losing both of her parents and her move to a new country without her family by her side. When the pain on the right side of her tongue increased to a point that made it difficult to eat or brush her teeth, her doctor decided to take a biopsy, and in March 2019, he informed her of the diagnosis.

“It was the most frightening thing I’ve ever felt in my life,” she said.

A week later, Angie had surgery to remove the right portion of her tongue, which contained the cancerous tissue, as well as 21 lymph nodes on the right side of her neck . A further analysis of the lymph nodes showed evidence of cancer, so her oncologist followed up with a treatment plan.

The toll of Angie’s treatment for oral cancer

Following her surgery and throughout treatment, Angie experienced a burning feeling in her mouth and throat, and it became extremely difficult for her to speak or eat – two of her favorite activities. Instead, she relied on a feeding tube for several months to receive her meals.

Though Angie was eventually able to resume eating normally, her sense of taste was impaired for a year after she finished treatment. The fact that chocolate, one of her favorite foods, tasted disgusting to her was heartbreaking.

“The doctor told me that he didn’t think I’d ever be able to speak well again. I told him that wasn’t an option because I love talking too much.”

— Angie Rosario

When Angie started to feel a deep depression, she prioritized her mental health and sought treatment from a psychologist, who taught her to focus on the present. Her psychologist encouraged her to visualize herself as a strong and healthy woman.

“I always say cancer was my teacher; It taught me how to live. If you have air in your lungs, you have everything you need,” Angie said.

Strong support and a welcome party from her work family

Angie is grateful for the science and research that helped play a part in her treatment. As of her last doctor’s visit, she remains healthy with no evidence of disease. Angie credits her work family at MSD for supporting her through much of her recovery. With the recent loss of her parents, her co-workers came to her aid with powerful emotional support that helped her through the toughest times. A lifelong collector of superhero toys, Angie came back to the office to find her desk covered in dolls, figurines and other gifts. Inspired by Angie’s courage, her colleagues even gave her a super-nickname: ‘Wonder Angie.’

Angie's desk filled with toys
Coworkers come together in conference room with treats

“I’m thankful for the science and medicine that helped save my life,” Angie said. “I can talk without pain, and that’s amazing. I can brush my teeth every day, and that’s amazing. I can eat, and that’s amazing.”

Angie has recovered her sense of taste for the most part, and can enjoy chocolate once again.

Health Awareness

Update to supply issue regarding OncoTICE

We know how important it is to get medicines to the people who need them and providing those medicines is at the center of what we do

January 24, 2024

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In 2012, MSD unexpectedly became the sole manufacturer of OncoTICE® in many countries around the world. Increasing global demand has outpaced our current maximum manufacturing capabilities. In recognition of the medical need for this product, MSD continues to operate at maximum production capacity. Due to the increasing global demand, MSD has been experiencing a supply shortage for OncoTICE. 

In October 2020, we announced our plans to construct a new manufacturing facility in Durham, North Carolina, U.S., to significantly expand our production capacity for OncoTICE. This investment reaffirms our longstanding commitment to producing this medicine, and all our medicines, for patients who need them.

If patients have questions regarding OncoTICE, they should speak with their physicians. Additional information related to the shortage, current allocation practices, and our efforts to increase supply, including construction of a new manufacturing site, is below.

FAQs: supply & availability of OncoTICE

What is the cause of the shortages and backorders for OncoTICE?

Since 2012, when MSD unexpectedly became the sole manufacturer of OncoTICE in many countries around the world, increasing global demand has outpaced our current maximum manufacturing capabilities. While the company has many years of experience producing OncoTICE, this medicine has a lengthy and inherently complex manufacturing process.

Prior to 2012, additional manufacturers supplied the U.S. market with OncoTICE, with MSD providing 30-40% of overall U.S. supply. As other manufacturers exited the U.S. market in 2012, MSD became the sole supplier to the U.S. and increased production of OncoTICE to the full extent of MSD’s current manufacturing capacity. These efforts enabled MSD to double supply of OncoTICE to the U.S. market despite being the only manufacturer, in recognition of the medical need for this product.

Can you provide an update on the new facility?

MSD is working to complete this project and meet patient needs in as timely a manner as possible. While this commitment is an important step in making sure that adequate supply of OncoTICE is available, completing construction, inspection, and regulatory approvals of a manufacturing facility may take approximately five to six years in total.

Construction is well underway, barring any unforeseen circumstances, the new facility is on track to the previously announced timeline and will be completed by late 2025 to late 2026. Supply will gradually increase over time following local market review and approvals.

Once this new facility is fully operational, we expect to triple our current manufacturing capacity of OncoTICE. We anticipate that this will meet the needs of physicians and their patients for the foreseeable future. The investment in this new manufacturing facility reaffirms MSD’s longstanding commitment to producing this medicine for patients.

Can you please describe how the allocation process works outside the U.S.?

MSD allocates available supply among markets based on historical demand patterns. This process is designed to proportionally allocate OncoTICE to minimize disruption to patient care as much as possible.

Where can I find more information about the availability of OncoTICE??

Patients:
Patients should reach out to their physician, as they are in the best position to answer questions about the availability of the medicine in their practice, and can inquire about the quantity and timing of product availability with their supplier.

Health care professionals:
Health care professionals with questions regarding allocation should contact their wholesaler or distributor.

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